- Disease Research
- Bioinformatics and Functional Genomics (textbook)
- Personnel and Contacts
- The Kennedy Krieger Institute
- Leonardo da Vinci
Welcome To The Pevsner Laboratory
Welcome to the laboratory of Jonathan Pevsner. Our lab studies the genetic basis of childhood brain disorders. We are located at the Kennedy Krieger Institute in Baltimore.
NEWS (June 27, 2015): The third edition of Bioinformatics and Functional Genomics is now in press. We'll launch the brand-new website at the time of publication. The book is almost entirely updated with a new chapter on next-generation sequencing, and it's filled with gentle introductions to R and a variety of command-line software. Look for the e-book in August and the hard copy soon after.
NEWS (June 27, 2015): We welcome several new people to the lab. Alexis Norris is a postdoctoral fellow who earned her Ph.D. in the Cellular and Molecular Medicine program at the Johns Hopkins School of Medicine. Welcome to Shruthi Bandyadkan who is currently getting her Master's degree in Biotechnology at Johns Hopkins! We also welcome summer students Morgan Marc (undergraduate at Johns Hopkins University), John Fissel (rotating from the Pathobiology graduate program), and high school students Grant Fisher (all the way from Texas) and Issy Newkirk.
NEWS (May 22, 2015): Jonathan gave the keynote speech for commencement at Johns Hopkins University (Krieger School of Arts & Sciences, Master's Degree ceremony). Congratulations to all the graduates! The speech was on genomics and Leonardo, and there were 1500 people in attendance. Click here to view.
NEWS (June 1, 2013): We have published a report on triPOD, a software tool written by graduate student Joseph Baugher (he is now a postdoctoral fellow at Johns Hopkins). triPOD analyzes SNP data from father/mother/child trios to identify mosaic abnormalities with extremely high sensitivity and specificity.
NEWS (May 8, 2013): Our laboratory recently reported the cause of Sturge-Weber syndrome (SWS), a rare neurocutaneous disorder. Patients with SWS also have a port-wine stain (PWS), a commonly occurring birthmark. Matt Shirley, a graduate student in the lab, analyzed six whole genome sequences from 3 individuals with SWS, comparing genomes derived from dissections of paired affected and unaffected regions of the body. This led to the identification of a mutation in GNAQ causing both SWS and PWS birthmarks.