Bioinformatics and Functional Genomics, 2nd Edition

Chapter 17: The Fungi

The fungi include include the best-characterized eukaryotic organism, the budding yeast Saccharomyces cerevisiae. In this chapter we analyze its genome, comprised of 16 chromosomes, and use bioinformatics tools such as the Saccharomyces Genome Database (SGD). We explore the phenomenon of whole-genome duplication that occurred in S. cerevisiase and other fungi, and discuss mechanisms of genome evolution. Finally, we survey the genomes of other fungi from Candida albicans and Neurospora crassa to the fission yeast Schizosaccharomyces pombe.

Web documents
Web Document 17-1
General Feature Format (.gff) file from MIPS for import into the UCSC Genome Browser
Web Document 17-2
18S ribosomal RNA sequences for phylogenetic analysis

Chapter 17 Resources
Powerpoint of the fungi lecture (November 2009)
Course site for Genomics (260.605, 2nd quarter 2009-2010). This companion site includes information such as the class schedule and assignments.
Key URLs: SGD, MIPS, NCBI fungi page, YGOB.